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Molecular detection of haemotropic Mycoplasma species in Rhipicephalus sanguineus tick species collected on lions (Panthera leo) from Ngorongoro Crater, Tanzania


Fyumagwa, R D; Simmler, P; Willi, B; Meli, M L; Sutter, A; Hoare, R; Dasen, G; Hofmann-Lehmann, R; Lutz, H (2008). Molecular detection of haemotropic Mycoplasma species in Rhipicephalus sanguineus tick species collected on lions (Panthera leo) from Ngorongoro Crater, Tanzania. South African Journal of Wildlife Research, 38(2):117-122.

Abstract

Haemotropic Mycoplasma species are pathogens that can cause haemolytic anaemia in susceptible mammalian species worldwide. The cause of haemolysis is due to membrane
damage through stimulation of IgM cold agglutinins production, which induces autoimmune haemolysis of infected erythrocytes. A study was conducted to establish the prevalence of Mycoplasma haemofelis, ‘ Candidatus Mycoplasma haemominutum’ and ‘ Candidatus M. turicensis’in ticks and the diversity of tick species that are possible vectors of the pathogens that can transmit the infection to wildlife in Ngorongoro Crater. Three real-time PCR assays
were used for the analysis of DNA pools ( n= 507) derived from 11 tick species. Mycoplasma haemofelis and ‘ Candidatus M. haemominutum’ were detected in Rhipicephalus
sanguineus.On average 19.7% and 12.9% of R. sanguineuswere PCR-positive for M. haemofelisand ‘ Candidatus M. haemominutum’, respectively. This tick species therefore represent an important reservoir for feline haemotropic Mycoplasma species in the crater. These organisms with their known pathological effects are probably one of the factors potentially exacerbating the severity of infection during the disease outbreak in wildlife and can have
undesirable outcome to wild cats like lions when under nutritional stress or in case of concurrent infection.

Abstract

Haemotropic Mycoplasma species are pathogens that can cause haemolytic anaemia in susceptible mammalian species worldwide. The cause of haemolysis is due to membrane
damage through stimulation of IgM cold agglutinins production, which induces autoimmune haemolysis of infected erythrocytes. A study was conducted to establish the prevalence of Mycoplasma haemofelis, ‘ Candidatus Mycoplasma haemominutum’ and ‘ Candidatus M. turicensis’in ticks and the diversity of tick species that are possible vectors of the pathogens that can transmit the infection to wildlife in Ngorongoro Crater. Three real-time PCR assays
were used for the analysis of DNA pools ( n= 507) derived from 11 tick species. Mycoplasma haemofelis and ‘ Candidatus M. haemominutum’ were detected in Rhipicephalus
sanguineus.On average 19.7% and 12.9% of R. sanguineuswere PCR-positive for M. haemofelisand ‘ Candidatus M. haemominutum’, respectively. This tick species therefore represent an important reservoir for feline haemotropic Mycoplasma species in the crater. These organisms with their known pathological effects are probably one of the factors potentially exacerbating the severity of infection during the disease outbreak in wildlife and can have
undesirable outcome to wild cats like lions when under nutritional stress or in case of concurrent infection.

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4 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Uncontrolled Keywords:haemotropic Mycoplasma, lions, Ngorongoro Crater, real-time PCR, ticks
Language:English
Date:October 2008
Deposited On:26 Feb 2009 15:35
Last Modified:05 Apr 2016 12:48
Publisher:South African Bureau for Scientific Publications
ISSN:0379-4369
Publisher DOI:https://doi.org/10.3957/0379-4369-38.2.117

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