UZH-Logo

Maintenance Infos

Extensive dystrophic pulmonary calcification in a Welsh pony mare


Schoster, Angelika; Bratton, Alexandra; McGurrin, M Kimberly J (2014). Extensive dystrophic pulmonary calcification in a Welsh pony mare. Journal of Equine Veterinary Science, 34(10):1234-1239.

Abstract

A 12-year-old Welsh pony mare was presented to the Ontario Veterinary College Teaching Hospital for signs of intermittent lethargy and increased abdominal breathing effort of 6 months duration. After physical examination, blood work, bronchoscopy, bronchoalveolar lavage, and diagnostic imaging of the thorax and attempted lung biopsy, pulmonary mineralization of unknown origin was suspected. The pony was treated palliative for 7 months with nonsteroidal anti-inflammatories and inhaled corticosteroids to treat accompanying airway inflammation before being euthanized because of poor prognosis and deterioration of clinical signs. On postmortem examination, the pulmonary architecture of the right and left cranioventral lung lobes, accessory lobe, and cranial potions of the left caudal lung lobe was replaced by hard mineralized tissue. No other organs other than a mediastinal lymph node and the lung were affected by mineralization. After decalcification, thick sheets of fibrous connective tissue organized into layers and lamellae replaced the normal architecture of the pulmonary parenchyma in more than 90% of the lung lobe examined on histopathology. The findings were consistent with generalized severe pulmonary fibrosis and dystrophic calcification.

A 12-year-old Welsh pony mare was presented to the Ontario Veterinary College Teaching Hospital for signs of intermittent lethargy and increased abdominal breathing effort of 6 months duration. After physical examination, blood work, bronchoscopy, bronchoalveolar lavage, and diagnostic imaging of the thorax and attempted lung biopsy, pulmonary mineralization of unknown origin was suspected. The pony was treated palliative for 7 months with nonsteroidal anti-inflammatories and inhaled corticosteroids to treat accompanying airway inflammation before being euthanized because of poor prognosis and deterioration of clinical signs. On postmortem examination, the pulmonary architecture of the right and left cranioventral lung lobes, accessory lobe, and cranial potions of the left caudal lung lobe was replaced by hard mineralized tissue. No other organs other than a mediastinal lymph node and the lung were affected by mineralization. After decalcification, thick sheets of fibrous connective tissue organized into layers and lamellae replaced the normal architecture of the pulmonary parenchyma in more than 90% of the lung lobe examined on histopathology. The findings were consistent with generalized severe pulmonary fibrosis and dystrophic calcification.

Altmetrics

Downloads

2 downloads since deposited on 08 Oct 2014
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2014
Deposited On:08 Oct 2014 11:48
Last Modified:05 Apr 2016 18:24
Publisher:Elsevier
ISSN:0737-0806
Publisher DOI:https://doi.org/10.1016/j.jevs.2014.07.002
Permanent URL: https://doi.org/10.5167/uzh-99195

Download

[img]
Content: Accepted Version
Filetype: PDF - Registered users only
Size: 1MB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations