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Role of molecular imaging in the era of personalized medicine: A review


Sala, Evis; Vargas, Hebert Alberto; Donati, O F; Weber, W A; Hricak, Hedvig (2014). Role of molecular imaging in the era of personalized medicine: A review. In: Luna, A; Vilanova, J C; da Cruz Jr, L C H; Rossi, S E. Functional Imaging in Oncology: Biophysical Basis and Technical Approaches. Berlin: Springer, 43-58.

Abstract

Molecular imaging allows the visual representation, characterization, and quantification of biological processes at the cellular and subcellular levels within intact living organisms. In oncology, it can be used to depict the abnormal molecules as well as the aberrant interactions of altered molecules on which cancers depend. Knowledge of the fundamental tissue, cellular, genomic, and molecular changes that form the hallmarks of cancer has led to the introduction of cancer therapies aimed at specific molecular targets. This chapter will illustrate why molecular imaging is an invaluable tool for developing and facilitating the appropriate use of such targeted treatments as well as conventional cancer treatments. Alone or combined with anatomic imaging, it is destined to play an increasingly important role in all stages of cancer care, from initial cancer detection through treatment and follow-up.

Molecular imaging allows the visual representation, characterization, and quantification of biological processes at the cellular and subcellular levels within intact living organisms. In oncology, it can be used to depict the abnormal molecules as well as the aberrant interactions of altered molecules on which cancers depend. Knowledge of the fundamental tissue, cellular, genomic, and molecular changes that form the hallmarks of cancer has led to the introduction of cancer therapies aimed at specific molecular targets. This chapter will illustrate why molecular imaging is an invaluable tool for developing and facilitating the appropriate use of such targeted treatments as well as conventional cancer treatments. Alone or combined with anatomic imaging, it is destined to play an increasingly important role in all stages of cancer care, from initial cancer detection through treatment and follow-up.

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Additional indexing

Item Type:Book Section, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2014
Deposited On:21 Oct 2014 15:24
Last Modified:05 Apr 2016 18:26
Publisher:Springer
ISBN:978-3-642-40412-2
Publisher DOI:https://doi.org/10.1007/978-3-642-40412-2_3

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