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Protocadherins: not just neuron glue, more too!


Stoeckli, Esther T (2014). Protocadherins: not just neuron glue, more too! Developmental Cell, 30(6):643-644.

Abstract

Selective fasciculation, in which axons navigate toward their targets along preexisting "pioneer" axons, requires specific cell-cell contacts to ensure proper target innervation. In this issue of Developmental Cell, Hayashi et al. (2014) show that the adhesion molecule Protocadherin-17 regulates selective fasciculation by promoting growth, rather than adhesion, of amygdala axons.

Abstract

Selective fasciculation, in which axons navigate toward their targets along preexisting "pioneer" axons, requires specific cell-cell contacts to ensure proper target innervation. In this issue of Developmental Cell, Hayashi et al. (2014) show that the adhesion molecule Protocadherin-17 regulates selective fasciculation by promoting growth, rather than adhesion, of amygdala axons.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2014
Deposited On:19 Nov 2014 11:23
Last Modified:14 Feb 2018 21:58
Publisher:Cell Press (Elsevier)
ISSN:1534-5807
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.devcel.2014.09.008
PubMed ID:25268171

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