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Nalbuphin in der Kinderanästhesie


Schultz-Machata, A-M; Becke, K; Weiss, M (2014). Nalbuphin in der Kinderanästhesie. Der Anästhesist, 63(2):135-143.

Abstract

Efficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a μ-receptor antagonist/κ-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.

Abstract

Efficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a μ-receptor antagonist/κ-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.

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2 citations in Web of Science®
3 citations in Scopus®
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Additional indexing

Other titles:Nalbuphine in pediatric anesthesia
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:February 2014
Deposited On:28 Nov 2014 12:12
Last Modified:08 Dec 2017 08:27
Publisher:Springer
ISSN:0003-2417
Publisher DOI:https://doi.org/10.1007/s00101-014-2293-z
PubMed ID:24504192

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