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Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA


Stradling, J R; Craig, S E; Kohler, M; Nicoll, D; Ayers, L; Nunn, A J; Bratton, D J (2015). Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA. Thorax, 70(2):181-182.

Abstract

The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13).
TRIAL REGISTRATION NUMBER: ISRCTN 34164388.

Abstract

The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13).
TRIAL REGISTRATION NUMBER: ISRCTN 34164388.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2015
Deposited On:09 Jan 2015 16:08
Last Modified:05 Apr 2016 18:42
Publisher:BMJ Publishing Group
ISSN:0040-6376
Publisher DOI:https://doi.org/10.1136/thoraxjnl-2014-205958
PubMed ID:25182045

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