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Hydrogels: From Membrane to Skin: Aqueous Permeation Control Through Light-Responsive Amphiphilic Polymer Co-Networks


Schöller, Katrin; Küpfer, Sabrina; Baumann, Lukas; Hoyer, Patrick M; de Courten, Damien; Rossi, René M; Vetushka, Aliaksei; Wolf, Martin; Bruns, Nico; Scherer, Lukas J (2014). Hydrogels: From Membrane to Skin: Aqueous Permeation Control Through Light-Responsive Amphiphilic Polymer Co-Networks. Advanced Functional Materials, 24(33):5308.

Abstract

Photochromic transparent membranes with reversible color switching and pronounced permeability change are demonstrated by K. Schöller, L. Scherer, and co-workers on page 5194. Lightresponsive spiropyran and spirooxazine derivatives are introduced to amphiphilic polymer co-networks to achieve the stimuli-responsive behavior of the delivery membrane and a similar heterophase structure and permeability like natural skin (shown in the picture). These properties are requested when applied as a “smart” lightresponsive membrane in a transdermal caffeinedelivery system for pre-term neonates.

Abstract

Photochromic transparent membranes with reversible color switching and pronounced permeability change are demonstrated by K. Schöller, L. Scherer, and co-workers on page 5194. Lightresponsive spiropyran and spirooxazine derivatives are introduced to amphiphilic polymer co-networks to achieve the stimuli-responsive behavior of the delivery membrane and a similar heterophase structure and permeability like natural skin (shown in the picture). These properties are requested when applied as a “smart” lightresponsive membrane in a transdermal caffeinedelivery system for pre-term neonates.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2014
Deposited On:10 Feb 2015 15:13
Last Modified:05 Apr 2016 18:52
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1616-301X
Publisher DOI:https://doi.org/10.1002/adfm.201470223
Official URL:http://onlinelibrary.wiley.com/doi/10.1002/adfm.201470223/abstract

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