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Totale Thyreoidektomie bei amiodaroninduzierter Hyperthyreose : Wann übersteigt das Risiko der konservativen Therapie das Risiko der chirurgischen Behandlung?


Meerwein, C; Vital, D; Greutmann, M; Schmid, C; Huber, G F (2014). Totale Thyreoidektomie bei amiodaroninduzierter Hyperthyreose : Wann übersteigt das Risiko der konservativen Therapie das Risiko der chirurgischen Behandlung? HNO, 62(2):100-105.

Abstract

Amiodarone plays a pivotal role in the treatment of ventricular and supraventricular arrhythmias. However, amiodarone-induced hyperthyroidism (AIH) is one of the most feared complications, which necessitates interdisciplinary treatment and careful balancing of the risks of conservative treatment against those of total thyroidectomy. In this article we discuss the pharmacological aspects of amiodarone and its diverse effects on the thyroid. Furthermore, we present diagnostic and therapeutic strategies and report our positive experiences with total thyroidectomy in patients with AIH. Particularly in patients for whom continuation of amiodarone treatment is compulsory, a well-timed total thyroidectomy is a reliable therapeutic option, with minimal complication rates and immediate amelioration of symptoms.

Abstract

Amiodarone plays a pivotal role in the treatment of ventricular and supraventricular arrhythmias. However, amiodarone-induced hyperthyroidism (AIH) is one of the most feared complications, which necessitates interdisciplinary treatment and careful balancing of the risks of conservative treatment against those of total thyroidectomy. In this article we discuss the pharmacological aspects of amiodarone and its diverse effects on the thyroid. Furthermore, we present diagnostic and therapeutic strategies and report our positive experiences with total thyroidectomy in patients with AIH. Particularly in patients for whom continuation of amiodarone treatment is compulsory, a well-timed total thyroidectomy is a reliable therapeutic option, with minimal complication rates and immediate amelioration of symptoms.

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Additional indexing

Other titles:Total thyroidectomy in patients with amiodarone-induced hyperthyroidism : When does the risk of conservative treatment exceed the risk of surgery?
Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Endocrinology and Diabetology
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2014
Deposited On:29 Jan 2015 09:16
Last Modified:05 Apr 2016 18:58
Publisher:Springer
ISSN:0017-6192
Publisher DOI:https://doi.org/10.1007/s00106-013-2806-0
PubMed ID:24549509

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