In the publication “Genetic associations with coronary heart disease: Meta-analyses of 12 candidate genetic variants” (Gene 531 (2013) 71–77) the authors perform six meta-analyses on single nucleotide polymorphisms located in different genes for an association with coronary heart disease (CHD). One of these genes is ALOX15 for which two large studies have been included in the analysis. While both of these studies investigated the association of the functional polymorphism rs34210653 with CHD, the authors interchanged the numbers of cases and controls in their analysis for one of the publications (Atherosclerosis. 2009 Jul;205(1):192–6). In contrast to what is displayed in their meta-analysis, this study included 2028 controls and 477 cases and showed a non-significant OR for CHD of 1.73 (CI 0.43–2.3). This changes the interpretation of the results dramatically because now all three large sub-studies investigating the association of rs34210653 with CHD reveal similar although sometimes non-significant risk increases for the minor allele.