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Choriocarcinoma with Metastasis in a Rabbit (Oryctolagus cuniculi)


Kaufmann-Bart, M; Fischer, I (2008). Choriocarcinoma with Metastasis in a Rabbit (Oryctolagus cuniculi). Veterinary Pathology, 45(1):77-79.

Abstract

A 3-year-old female rabbit (Oryctolagus cuniculi) presented with apathy and indisposition for 2–3 days. Palpation revealed a mass in the caudal abdomen, namely, in the wall of the uterus.
Ovariohysterectomy was performed, and the tissues were submitted for histopathologic examination.
The mass consisted of 3 different (trophoblastic, syncytiotrophoblastic, and cytotrophoblastic) neoplastic cell types originating from the uterus. Immunohistochemistry was positive for cytokeratin in all 3 neoplastic cell types, and the syncytiotrophoblasts were positive also for human chorionic
gonadotropin. Together these features allow the diagnosis choriocarcinoma. This report documents the first case of a spontaneous choriocarcinoma in a rabbit.

Abstract

A 3-year-old female rabbit (Oryctolagus cuniculi) presented with apathy and indisposition for 2–3 days. Palpation revealed a mass in the caudal abdomen, namely, in the wall of the uterus.
Ovariohysterectomy was performed, and the tissues were submitted for histopathologic examination.
The mass consisted of 3 different (trophoblastic, syncytiotrophoblastic, and cytotrophoblastic) neoplastic cell types originating from the uterus. Immunohistochemistry was positive for cytokeratin in all 3 neoplastic cell types, and the syncytiotrophoblasts were positive also for human chorionic
gonadotropin. Together these features allow the diagnosis choriocarcinoma. This report documents the first case of a spontaneous choriocarcinoma in a rabbit.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Pathology
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2008
Deposited On:21 Jan 2009 10:06
Last Modified:06 Dec 2017 17:06
Publisher:American College of Veterinary Pathologists
ISSN:0300-9858
Publisher DOI:https://doi.org/10.1354/vp.45-1-77

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