Header

UZH-Logo

Maintenance Infos

Comparison of ultrashort echo time sequences for MRI of an ancient mummified human hand


Özen, Ali Caglar; Ludwig, Ute; Öhrström, Lena Maria; Rühli, Frank Jakobus; Bock, Michael (2016). Comparison of ultrashort echo time sequences for MRI of an ancient mummified human hand. Magnetic Resonance in Medicine, 75(2):701-708.

Abstract

PURPOSE: To compare the three different short-echo time (TE) pulse sequences ultrashort echo time (UTE), point-wise encoding time reduction with radial acquisition (PETRA), and single point imaging (SPI) for MRI of ancient remains.
METHODS: MRI of mummies is challenging due to the extremely low water content and the very short transverse relaxation times T2 *. To overcome the signal loss associated with the short T2 *, three pulse sequences with very short TEs were compared. MR images of an ancient mummified human hand were acquired at field strengths of 1.5 Tesla (T) and 3T using home-made solenoid Tx/Rx radiofrequency (RF) coils.
RESULTS: In all MR images, tissues could be differentiated and anatomical structures such as bones and tendons were clearly identified. Skin with embalming resin was hyperintense in MRI, whereas it appeared iso-intense in computed tomography. PETRA has the highest signal to noise ratio. With UTE, short scan times and a homogeneous RF excitation can be achieved, and blurring is less pronounced than with PETRA. SPI shows no blurring artifacts; however, it requires long scan times.
CONCLUSION: This work provided an initial analysis for the optimization of imaging protocols for paleoradiology studies with MRI, and, ultimately, for MRI of tissue with extremely short T2 *.

Abstract

PURPOSE: To compare the three different short-echo time (TE) pulse sequences ultrashort echo time (UTE), point-wise encoding time reduction with radial acquisition (PETRA), and single point imaging (SPI) for MRI of ancient remains.
METHODS: MRI of mummies is challenging due to the extremely low water content and the very short transverse relaxation times T2 *. To overcome the signal loss associated with the short T2 *, three pulse sequences with very short TEs were compared. MR images of an ancient mummified human hand were acquired at field strengths of 1.5 Tesla (T) and 3T using home-made solenoid Tx/Rx radiofrequency (RF) coils.
RESULTS: In all MR images, tissues could be differentiated and anatomical structures such as bones and tendons were clearly identified. Skin with embalming resin was hyperintense in MRI, whereas it appeared iso-intense in computed tomography. PETRA has the highest signal to noise ratio. With UTE, short scan times and a homogeneous RF excitation can be achieved, and blurring is less pronounced than with PETRA. SPI shows no blurring artifacts; however, it requires long scan times.
CONCLUSION: This work provided an initial analysis for the optimization of imaging protocols for paleoradiology studies with MRI, and, ultimately, for MRI of tissue with extremely short T2 *.

Statistics

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Evolutionary Medicine
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2016
Deposited On:07 Apr 2015 11:12
Last Modified:05 Apr 2016 19:12
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0740-3194
Publisher DOI:https://doi.org/10.1002/mrm.25651
PubMed ID:25752671

Download

Full text not available from this repository.
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations