Header

UZH-Logo

Maintenance Infos

Oral infections: clinical and biological perspectives


Belibasakis, Georgios N; Mylonakis, Eleftherios (2015). Oral infections: clinical and biological perspectives. Virulence, 6(3):173-176.

Abstract

The oral cavity is a specialized ecological niche of the human body and forms a continuum with the digestive and respiratory system. The vastly diverse endogenous microbiota of the oral cavity is collectively referred to as the "oral microbiome". It has been, and continues to be, explored by numerous cultivation or culture-independent methods, yielding more that 600 individual taxa (1) . They show tropism for different microhabitats, but may also show differential associations with oral health or disease. Commensal oral microbiota live in a symbiotic relationship with the host, which is crucial for the maintenance of oral health (2) . Yet, disruption of this tight relationship by various factors will result in dysbiosis, allowing for the survival and establishment of a more virulent pathobiotic polymicrobial community that may impair the efficient immune response (3, 4) . Clinically, these events could manifest as an oral infectious diseases.

Abstract

The oral cavity is a specialized ecological niche of the human body and forms a continuum with the digestive and respiratory system. The vastly diverse endogenous microbiota of the oral cavity is collectively referred to as the "oral microbiome". It has been, and continues to be, explored by numerous cultivation or culture-independent methods, yielding more that 600 individual taxa (1) . They show tropism for different microhabitats, but may also show differential associations with oral health or disease. Commensal oral microbiota live in a symbiotic relationship with the host, which is crucial for the maintenance of oral health (2) . Yet, disruption of this tight relationship by various factors will result in dysbiosis, allowing for the survival and establishment of a more virulent pathobiotic polymicrobial community that may impair the efficient immune response (3, 4) . Clinically, these events could manifest as an oral infectious diseases.

Statistics

Citations

2 citations in Web of Science®
2 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

37 downloads since deposited on 16 Apr 2015
4 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Institute of Oral Biology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 April 2015
Deposited On:16 Apr 2015 08:46
Last Modified:07 Aug 2017 00:28
Publisher:Landes Bioscience
ISSN:2150-5594
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1080/21505594.2015.1025191
PubMed ID:25830413

Download

Preview Icon on Download
Preview
Content: Accepted Version
Filetype: PDF
Size: 80kB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations