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Hepatitis A and hepatitis B: risks compared with other vaccine preventable diseases and immunization recommendations


Steffen, Robert (1993). Hepatitis A and hepatitis B: risks compared with other vaccine preventable diseases and immunization recommendations. Vaccine, 11(5):518-520.

Abstract

The incidence rate of hepatitis A is 3(-6)/1000 per month of stay in a developing country in unprotected travellers. Tramps and other persons feeding themselves under bad hygienic conditions have a rate of 20/1000. In many industrialized countries, persons below the age of 50 years have a seroprevalence rate of anti-HAV < 20%. Hepatitis A morbidity and mortality rates in travellers are far greater than those of any other vaccine-preventable infection in travellers, with the exception that hepatitis B shows a slightly greater mortality rate in expatriates. Future studies will determine the role of hepatitis C and E. Typhoid fever shows an incidence rate of 0.3/1000 in foreigners on the Indian subcontinent, and in many parts of North and West Africa, excluding Tunisia; in other parts of the Third World it is tenfold lower. In poliomyelitis, tetanus, diphtheria, cholera, rabies and Japanese encephalitis the incidence rate is < or = 0.002/1000.

Abstract

The incidence rate of hepatitis A is 3(-6)/1000 per month of stay in a developing country in unprotected travellers. Tramps and other persons feeding themselves under bad hygienic conditions have a rate of 20/1000. In many industrialized countries, persons below the age of 50 years have a seroprevalence rate of anti-HAV < 20%. Hepatitis A morbidity and mortality rates in travellers are far greater than those of any other vaccine-preventable infection in travellers, with the exception that hepatitis B shows a slightly greater mortality rate in expatriates. Future studies will determine the role of hepatitis C and E. Typhoid fever shows an incidence rate of 0.3/1000 in foreigners on the Indian subcontinent, and in many parts of North and West Africa, excluding Tunisia; in other parts of the Third World it is tenfold lower. In poliomyelitis, tetanus, diphtheria, cholera, rabies and Japanese encephalitis the incidence rate is < or = 0.002/1000.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1993
Deposited On:21 May 2015 14:18
Last Modified:05 Apr 2016 19:15
Publisher:Elsevier
ISSN:0264-410X
Publisher DOI:https://doi.org/10.1016/0264-410X(93)90221-I
PubMed ID:8387717

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