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Cerebellar cysts in children: a pattern recognition approach


Boltshauser, Eugen; Scheer, Ianina; Huisman, Thierry A G M; Poretti, Andrea (2015). Cerebellar cysts in children: a pattern recognition approach. Cerebellum, 14(3):308-316.

Abstract

Cerebellar cysts may be seen in selected genetic disorders and acquired anomalies. Here, we review our experience, excluding cystic tumors and parasitic cysts. The pathogenesis is heterogeneous: Cysts may involve/represent normal structures (e.g., Virchow-Robin spaces), be "destructive" (such as in some types of pontocerebellar hypoplasias), "malformative" (such as in some forms of congenital muscular dystrophies and GPR56-related migration disorders), or "disruptive" (such as in some cerebellar dysplasias). The provided checklist may be useful in deciding targeted diagnostic workup.

Abstract

Cerebellar cysts may be seen in selected genetic disorders and acquired anomalies. Here, we review our experience, excluding cystic tumors and parasitic cysts. The pathogenesis is heterogeneous: Cysts may involve/represent normal structures (e.g., Virchow-Robin spaces), be "destructive" (such as in some types of pontocerebellar hypoplasias), "malformative" (such as in some forms of congenital muscular dystrophies and GPR56-related migration disorders), or "disruptive" (such as in some cerebellar dysplasias). The provided checklist may be useful in deciding targeted diagnostic workup.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:June 2015
Deposited On:27 Aug 2015 14:53
Last Modified:14 Feb 2018 09:21
Publisher:Springer
ISSN:1473-4222
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s12311-014-0633-9
PubMed ID:25504001

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