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Towards Tris(diimine)-Ru(II) and Bis(quinoline) Re(I)(CO)3 Complexes as Photoactivated Anticancer Drug Candidates


Joshi, Tanmaya; Gasser, Gilles (2015). Towards Tris(diimine)-Ru(II) and Bis(quinoline) Re(I)(CO)3 Complexes as Photoactivated Anticancer Drug Candidates. Synlett, 26(3):275-284.

Abstract

The clinical success of cisplatin continues to inspire the development of metal-based anticancer drug candidates. This article is meant to present the current state-of-the-art and science of ruthenium(II)- and rhenium(I)-based anticancer drug candidates born out of our work in this field. Our recent efforts to elicit photoactivation of intact (organo)metallic anticancer drug candidates as a promising way for commanding their activity within cancer cells are also briefly summarized.

Abstract

The clinical success of cisplatin continues to inspire the development of metal-based anticancer drug candidates. This article is meant to present the current state-of-the-art and science of ruthenium(II)- and rhenium(I)-based anticancer drug candidates born out of our work in this field. Our recent efforts to elicit photoactivation of intact (organo)metallic anticancer drug candidates as a promising way for commanding their activity within cancer cells are also briefly summarized.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Language:English
Date:2015
Deposited On:11 Nov 2015 14:43
Last Modified:21 Nov 2017 18:05
Publisher:Georg Thieme Verlag
ISSN:1437-2096
Publisher DOI:https://doi.org/10.1055/s-0034-1379426

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