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Congenital cytomegalovirus infection


D'Oronzio, U; Arlettaz, R; Hagmann, C (2015). Congenital cytomegalovirus infection. http://www.neonet.ch/en/: Swiss Society of Neonatology.

Abstract

Introduction: Early pregnancy of this 31-year-old 3G/3P mother was uneventful. At 22 weeks of gestation, reduced amniotic fluid, hyperechogenic bowel and scaphocephaly were seen on antenatal ultrasound. The mother was referred to the fetal medicine unit at our hospital for further evaluation. Amniocentesis revealed a normal female karyotype. Maternal TORCH screening showed primary cytomegalovirus (CMV) infection with positive IgG and IgM titers, and a viral load of 1.2 million DNA copies per ml. Amniotic fluid testing confirmed fetal infection with positive culture, antigen testing and polymerase chain reaction (PCR).

Abstract

Introduction: Early pregnancy of this 31-year-old 3G/3P mother was uneventful. At 22 weeks of gestation, reduced amniotic fluid, hyperechogenic bowel and scaphocephaly were seen on antenatal ultrasound. The mother was referred to the fetal medicine unit at our hospital for further evaluation. Amniocentesis revealed a normal female karyotype. Maternal TORCH screening showed primary cytomegalovirus (CMV) infection with positive IgG and IgM titers, and a viral load of 1.2 million DNA copies per ml. Amniotic fluid testing confirmed fetal infection with positive culture, antigen testing and polymerase chain reaction (PCR).

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Additional indexing

Item Type:Scientific Publication in Electronic Form
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:May 2015
Deposited On:07 Jan 2016 09:34
Last Modified:08 Dec 2017 16:31
Publisher:Swiss Society of Neonatology
Series Name:Cases of the Month (COTMs)
Free access at:Official URL. An embargo period may apply.
Official URL:http://www.neonet.ch/files/7414/2988/1978/Cotm_Mai_2015.pdf
Related URLs:http://www.neonet.ch/en/case-month/archive/ (Publisher)

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