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Long term follow-up after endovascular brachytherapy of femoro-popliteal arteries


Thalhammer, Christoph; Alvarez, Elena; Husmann, Marc; Staub, Daniel; Kaspar, Mathias; Aschwanden, Markus; Amann-Vesti, Beatrice R (2015). Long term follow-up after endovascular brachytherapy of femoro-popliteal arteries. Clinical Hemorheology and Microcirculation, 61(2):251-257.

Abstract

To perform a long term follow-up after endovascular brachytherapy (EVBT) and balloon angioplasty (PTA) regarding vessel patency and diameter. EVBT had been successfully used to decrease restenosis in short term, but long term data are lacking. Participants of a randomized study comparing EVBT and balloon angioplasty alone were invited for follow-up examination ten years after intervention. Using a standardized protocol measurement of the patency and vessel diameter was performed of femoral and popliteal arteries. 44 patients were included, 21 had been treated with EVBT and 23 had received PTA alone. Target lesion patency was similar between the two groups (90.5% vs. 87.0%). Vessel diameter of the target lesion was significantly greater in the EVBT group (6.4 mm, range 3.9-9.9) compared to the controls (5.0 mm, range 3.1-7.4; p = 0.002). Ten years after EVBT of femoro-popliteal arteries vessel diameter is significantly increased whereas patency rate is not different compared to angioplasty alone.

Abstract

To perform a long term follow-up after endovascular brachytherapy (EVBT) and balloon angioplasty (PTA) regarding vessel patency and diameter. EVBT had been successfully used to decrease restenosis in short term, but long term data are lacking. Participants of a randomized study comparing EVBT and balloon angioplasty alone were invited for follow-up examination ten years after intervention. Using a standardized protocol measurement of the patency and vessel diameter was performed of femoral and popliteal arteries. 44 patients were included, 21 had been treated with EVBT and 23 had received PTA alone. Target lesion patency was similar between the two groups (90.5% vs. 87.0%). Vessel diameter of the target lesion was significantly greater in the EVBT group (6.4 mm, range 3.9-9.9) compared to the controls (5.0 mm, range 3.1-7.4; p = 0.002). Ten years after EVBT of femoro-popliteal arteries vessel diameter is significantly increased whereas patency rate is not different compared to angioplasty alone.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Angiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:9 September 2015
Deposited On:12 Jan 2016 10:07
Last Modified:08 Dec 2017 16:42
Publisher:I O S Press
ISSN:1386-0291
Publisher DOI:https://doi.org/10.3233/CH-151997
PubMed ID:26410876

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