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Atypical meningoma: current management dilemmas and prospective clinical trials


Jenkinson, Michael D; Weber, Damien C; Haylock, Brian J; Mallucci, Conor L; Zakaria, Rasheed; Javadpour, Mohsen (2015). Atypical meningoma: current management dilemmas and prospective clinical trials. Journal of Neuro-Oncology, 121(1):1-7.

Abstract

Atypical meningioma is an intermediate grade tumour with a greater risk of recurrence following surgical resection. Changes to the WHO classification have resulted in an increased reporting of these tumours. The role of early adjuvant radiotherapy after gross total resection has not been clearly defined and the literature evidence is of poor quality providing conflicting information. This review assesses the evidence for current clinical practice, management dilemmas and the need for prospective clinical trials for atypical meningioma.

Abstract

Atypical meningioma is an intermediate grade tumour with a greater risk of recurrence following surgical resection. Changes to the WHO classification have resulted in an increased reporting of these tumours. The role of early adjuvant radiotherapy after gross total resection has not been clearly defined and the literature evidence is of poor quality providing conflicting information. This review assesses the evidence for current clinical practice, management dilemmas and the need for prospective clinical trials for atypical meningioma.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Radiation Oncology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:January 2015
Deposited On:12 Jan 2016 13:00
Last Modified:14 Feb 2018 10:29
Publisher:Springer
ISSN:0167-594X
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/s11060-014-1620-1
PubMed ID:25258253

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