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Recent trends in the development of vitamin B12derivatives for medicinal applications


Zelder, Felix (2015). Recent trends in the development of vitamin B12derivatives for medicinal applications. Chemical Communications, 51(74):14004-14017.

Abstract

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for medicinal applications. The following topics are emphasized: (1) the development of aquacorrinoids for cyanide detection and detoxification, (2) the use of vitamin B12 conjugates and (3) antivitamins B12 for therapy and diagnosis, and (4) the design of corrinoids as activators of soluble guanylyl cyclase (sGC).

Abstract

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for medicinal applications. The following topics are emphasized: (1) the development of aquacorrinoids for cyanide detection and detoxification, (2) the use of vitamin B12 conjugates and (3) antivitamins B12 for therapy and diagnosis, and (4) the design of corrinoids as activators of soluble guanylyl cyclase (sGC).

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Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Language:English
Date:25 September 2015
Deposited On:13 Jan 2016 15:57
Last Modified:14 Feb 2018 10:31
Publisher:Royal Society of Chemistry
ISSN:1359-7345
OA Status:Closed
Publisher DOI:https://doi.org/10.1039/C5CC04843E

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