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The good, the bad, or the pretty: IL-17 builds lymphoid tissues in the brain


Becher, Burkhard (2015). The good, the bad, or the pretty: IL-17 builds lymphoid tissues in the brain. Immunity, 43(6):1033-1034.

Abstract

Lymph node development depends on well-orchestrated interactions between lymphoid tissue inducer cells and stromal cells. In this issue of Immunity, Pikor and colleagues (2015) find that signals from IL-17-producing T helper cells can alter the stromal microenvironment of the inflamed brain to generate a neo-lymphoid organ that drives further inflammation.

Abstract

Lymph node development depends on well-orchestrated interactions between lymphoid tissue inducer cells and stromal cells. In this issue of Immunity, Pikor and colleagues (2015) find that signals from IL-17-producing T helper cells can alter the stromal microenvironment of the inflamed brain to generate a neo-lymphoid organ that drives further inflammation.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Experimental Immunology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:15 December 2015
Deposited On:01 Feb 2016 12:36
Last Modified:05 Apr 2016 19:56
Publisher:Cell Press (Elsevier)
ISSN:1074-7613
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.immuni.2015.11.021
PubMed ID:26682978

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