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Nonotogenic skull base osteomyelitis in children: two cases and a review of the literature


Trück, Johannes; Thompson, Ameeka; Dwivedi, Reena; Segal, Shelley; Anand, Geetha; Kelly, Dominic F (2015). Nonotogenic skull base osteomyelitis in children: two cases and a review of the literature. The Pediatric Infectious Disease Journal, 34(9):1025-1027.

Abstract

Skull base osteomyelitis is a rare condition in childhood and can be described according to whether it is associated with spread of infection from the middle ear (otogenic) or not (nonotogenic). Early recognition of this serious disease and prompt treatment are key to preventing extension to adjacent vascular and nervous system structures. Diagnosis can be challenging due to the variable presentation of the disease and potentially subtle radiological appearances. We present 2 cases of nonotogenic skull base osteomyelitis in childhood both affecting the clivus and review the 6 cases previously described. Both children presented with fever, headache and neck stiffness and responded well to medical management alone; detailed imaging was key to making a diagnosis.

Abstract

Skull base osteomyelitis is a rare condition in childhood and can be described according to whether it is associated with spread of infection from the middle ear (otogenic) or not (nonotogenic). Early recognition of this serious disease and prompt treatment are key to preventing extension to adjacent vascular and nervous system structures. Diagnosis can be challenging due to the variable presentation of the disease and potentially subtle radiological appearances. We present 2 cases of nonotogenic skull base osteomyelitis in childhood both affecting the clivus and review the 6 cases previously described. Both children presented with fever, headache and neck stiffness and responded well to medical management alone; detailed imaging was key to making a diagnosis.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:September 2015
Deposited On:28 Jan 2016 14:05
Last Modified:08 Dec 2017 17:36
Publisher:Lippincott Williams & Wilkins
ISSN:0891-3668
Publisher DOI:https://doi.org/10.1097/INF.0000000000000782
PubMed ID:26090573

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