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Stromelysin activity in canine cranial cruciate ligament rupture


Spreng, B; Sigrist, Nadja; von Rechenberg, Brigitte; Busato, André; Schawalder, P (1999). Stromelysin activity in canine cranial cruciate ligament rupture. Veterinary and Comparative Orthopaedics and Traumatology, (4):10-16.

Abstract

Stromelysin, one of the major metalloproteinases degrades articular cartilage mainly by cleavage of proteoglycans. Increased levels of stromelysin could be demonstrated in cartilage of stifle joints from dogs with naturally acquired cranial cruciate ligament rupture using a radioimmunoassay. There was an indication in this study that the activity of stromelysin is associated with the severity of osteoarthritic changes.

Abstract

Stromelysin, one of the major metalloproteinases degrades articular cartilage mainly by cleavage of proteoglycans. Increased levels of stromelysin could be demonstrated in cartilage of stifle joints from dogs with naturally acquired cranial cruciate ligament rupture using a radioimmunoassay. There was an indication in this study that the activity of stromelysin is associated with the severity of osteoarthritic changes.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Uncontrolled Keywords:osteoarthritis, dog, cartilage, stromelysin
Language:English
Date:1999
Deposited On:22 Mar 2016 08:37
Last Modified:08 Dec 2017 19:18
Publisher:Schattauer
ISSN:0932-0814

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