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Embodied neurology: an integrative framework for neurological disorders


Freund, Patrick; Friston, Karl J; Thompson, Alan J; Stephan, Klaas E; Ashburner, John; Bach, Dominik R; Nagy, Zoltan; Helms, Gunther; Draganski, Bogdan; Mohammadi, Siawoosh; Schwab, Martin E; Curt, Armin; Weiskopf, Nikolaus (2016). Embodied neurology: an integrative framework for neurological disorders. Brain, 139(6):1855-1861.

Abstract

From a systems biology perspective, the brain and spinal cord are interwoven with the body: they are 'embodied'. Freund et al. propose an integrative framework based on biophysical models that aims to characterize neurological disorders and minimize their impact on patients by considering functional interactions between supra-spinal, spinal and peripheral regions simultaneously.

Abstract

From a systems biology perspective, the brain and spinal cord are interwoven with the body: they are 'embodied'. Freund et al. propose an integrative framework based on biophysical models that aims to characterize neurological disorders and minimize their impact on patients by considering functional interactions between supra-spinal, spinal and peripheral regions simultaneously.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Balgrist University Hospital, Swiss Spinal Cord Injury Center
04 Faculty of Medicine > Institute of Biomedical Engineering
04 Faculty of Medicine > Brain Research Institute
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Uncontrolled Keywords:Biophysical models; dynamic causal modelling; multiscale interactions; neuroimaging; precision neurology
Language:English
Date:2016
Deposited On:29 Apr 2016 17:16
Last Modified:10 Aug 2017 13:15
Publisher:Oxford University Press
ISSN:0006-8950
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/brain/aww076
Official URL:http://brain.oxfordjournals.org/content/early/2016/04/20/brain.aww076
PubMed ID:27105896

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