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Nephroblastome : Praktisch immer in Studien!


Bode, Peter K; Moch, Holger (2016). Nephroblastome : Praktisch immer in Studien! Der Pathologe, 37(2):166-171.

Abstract

Nephroblastomas are the most commonly occurring renal neoplasms in childhood and are treated almost exclusively in clinical trials. An important factor for further therapeutic management is the pathological evaluation of the nephrectomy specimen. Tumor stage and risk group classification are the most crucial parameters. An independent assessment of the tumor by a reference pathology center is an essential standard procedure. Although many molecular genetic discoveries have been made in nephroblastomas over recent years, molecular parameters do not (yet) play a role in treatment stratification.

Abstract

Nephroblastomas are the most commonly occurring renal neoplasms in childhood and are treated almost exclusively in clinical trials. An important factor for further therapeutic management is the pathological evaluation of the nephrectomy specimen. Tumor stage and risk group classification are the most crucial parameters. An independent assessment of the tumor by a reference pathology center is an essential standard procedure. Although many molecular genetic discoveries have been made in nephroblastomas over recent years, molecular parameters do not (yet) play a role in treatment stratification.

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Additional indexing

Other titles:Nephroblastomas : Almost exclusively in clinical trials!
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:March 2016
Deposited On:17 May 2016 08:18
Last Modified:23 Nov 2017 21:06
Publisher:Springer
ISSN:0172-8113
Publisher DOI:https://doi.org/10.1007/s00292-016-0148-x
PubMed ID:26942729

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