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EEG coherence in Alzheimer disease


Besthorn, C; Förstl, H; Geiger-Kabisch, C; Sattel, H; Gasser, Theo; Schreiter-Gasser, Ursula (1994). EEG coherence in Alzheimer disease. Electroencephalography and Clinical Neurophysiology, 90(3):242-245.

Abstract

A novel approach is introduced to examine EEG coherence in different frequency bands of 17 locations from the 10-20 system. Fifty patients with clinically diagnosed Alzheimer's disease were compared with 42 age-approximated non-demented controls. We determined the average coherence between individual electrodes and all neighbouring electrodes. Coherence was decreased in the sample of demented patients and this effect was most pronounced in the frontal and central derivations of the theta, alpha and beta frequency bands. The results can be interpreted as the effects of neuronal loss and neocortical disconnection.

Abstract

A novel approach is introduced to examine EEG coherence in different frequency bands of 17 locations from the 10-20 system. Fifty patients with clinically diagnosed Alzheimer's disease were compared with 42 age-approximated non-demented controls. We determined the average coherence between individual electrodes and all neighbouring electrodes. Coherence was decreased in the sample of demented patients and this effect was most pronounced in the frontal and central derivations of the theta, alpha and beta frequency bands. The results can be interpreted as the effects of neuronal loss and neocortical disconnection.

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Additional indexing

Item Type:Journal Article, not refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:March 1994
Deposited On:10 Jun 2016 09:31
Last Modified:12 Jun 2016 10:09
Publisher:Elsevier
ISSN:0013-4694
Publisher DOI:https://doi.org/10.1016/0013-4694(94)90095-7
PubMed ID:7511505

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