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A note concerning the caries preventive effect of Duraphat


Helfenstein, Ulrich; Steiner, M (1994). A note concerning the caries preventive effect of Duraphat. Community Dentistry and Oral Epidemiology, 22(1):6-7.

Abstract

In a previous article (1) we analyzed a series of eight studies concerned with the effect of Duraphat in the prevention of dental caries by means of meta-analysis. A random effects model was used to estimate an overall effect size of caries reduction R and the corresponding confidence interval. In the present short communication we complement this previous study by neglecting the within study variation to the overall variation which is dominated by between study variation. This allows us to include a larger number of studies and thus make fuller use of the available information. We estimate nonparametrical confidence intervals for effect sizes (caries reduction) by means of the "bootstrap method". The overall caries reduction R on permanent teeth (14 studies) was estimated to be: R = 0.38 (95%-CI: 0.25-0.50).

Abstract

In a previous article (1) we analyzed a series of eight studies concerned with the effect of Duraphat in the prevention of dental caries by means of meta-analysis. A random effects model was used to estimate an overall effect size of caries reduction R and the corresponding confidence interval. In the present short communication we complement this previous study by neglecting the within study variation to the overall variation which is dominated by between study variation. This allows us to include a larger number of studies and thus make fuller use of the available information. We estimate nonparametrical confidence intervals for effect sizes (caries reduction) by means of the "bootstrap method". The overall caries reduction R on permanent teeth (14 studies) was estimated to be: R = 0.38 (95%-CI: 0.25-0.50).

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10 citations in Web of Science®
12 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:February 1994
Deposited On:10 Jun 2016 14:40
Last Modified:08 Dec 2017 19:41
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0301-5661
Publisher DOI:https://doi.org/10.1111/j.1600-0528.1994.tb01560.x
PubMed ID:8143445

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