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Treat-to-target versus dose-adapted statin treatment of cholesterol to reduce cardiovascular risk


Müller-Wieland, Dirk; Assmann, Gerd; Carmena, Rafael; Davignon, Jean; von Eckardstein, Arnold; Farinaro, Eduardo; Greten, Heiner; Olsson, Anders G; Riesen, Walter F; Shlyakhto, Evgenyi (2016). Treat-to-target versus dose-adapted statin treatment of cholesterol to reduce cardiovascular risk. European Journal of Preventive Cardiology, 23(3):275-281.

Abstract

Clinical guidelines should be based on the best available evidence and are of great importance for patient care and disease prevention. In this respect, the 2013 American College of Cardiology/American Heart Association report is highly appreciated and well-recognized. The report included critical questions concerning hypercholesterolaemia, but its translation into a clinical guideline initiated intense debate worldwide because of the recommendation to switch from a treat-to-target approach for low-density-lipoprotein-cholesterol to a statin dose-based strategy.

Abstract

Clinical guidelines should be based on the best available evidence and are of great importance for patient care and disease prevention. In this respect, the 2013 American College of Cardiology/American Heart Association report is highly appreciated and well-recognized. The report included critical questions concerning hypercholesterolaemia, but its translation into a clinical guideline initiated intense debate worldwide because of the recommendation to switch from a treat-to-target approach for low-density-lipoprotein-cholesterol to a statin dose-based strategy.

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4 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Clinical Chemistry
Dewey Decimal Classification:610 Medicine & health
540 Chemistry
Language:English
Date:February 2016
Deposited On:05 Jul 2016 14:35
Last Modified:10 Jul 2016 05:23
Publisher:Sage Publications Ltd.
ISSN:2047-4873
Publisher DOI:https://doi.org/10.1177/2047487314567001
PubMed ID:25595550

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