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Spinal metastases: Is stereotactic body radiation therapy supported by evidences?


De Bari, Berardino; Alongi, Filippo; Mortellaro, Gianluca; Mazzola, Rosario; Schiappacasse, Luis; Guckenberger, Matthias (2016). Spinal metastases: Is stereotactic body radiation therapy supported by evidences? Critical Reviews in Oncology/Hematology, 98:147-158.

Abstract

Stereotactic body radiotherapy (SBRT) is becoming widely adopted in the treatment of primary and secondary tumors. Spinal bone metastases are frequently discovered in cancer patients, and in the past have been usually treated with a palliative goal. Nevertheless, in some particular clinical settings, such as oligometastatic patients and/or those with a long life expectancy, spinal SBRT could be considered a valid therapeutic option to obtain long-lasting palliation and, when possible, with a curative goal. This review aims to summarize available clinical and dosimetric data of published studies about spinal SBRT.

Abstract

Stereotactic body radiotherapy (SBRT) is becoming widely adopted in the treatment of primary and secondary tumors. Spinal bone metastases are frequently discovered in cancer patients, and in the past have been usually treated with a palliative goal. Nevertheless, in some particular clinical settings, such as oligometastatic patients and/or those with a long life expectancy, spinal SBRT could be considered a valid therapeutic option to obtain long-lasting palliation and, when possible, with a curative goal. This review aims to summarize available clinical and dosimetric data of published studies about spinal SBRT.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Radiation Oncology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:February 2016
Deposited On:03 Feb 2017 15:27
Last Modified:04 Feb 2017 08:46
Publisher:Elsevier
ISSN:1040-8428
Publisher DOI:https://doi.org/10.1016/j.critrevonc.2015.11.002
PubMed ID:26597017

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