Header

UZH-Logo

Maintenance Infos

Machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines


Karangwa, S A; Dutkowski, P; Fontes, P; Friend, P J; Guarrera, J V; Markmann, J F; Mergental, H; Minor, T; Quintini, C; Selzner, M; Uygun, K; Watson, C J; Porte, R J (2016). Machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines. American Journal of Transplantation, 16(10):2932-2942.

Abstract

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.

Abstract

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.

Statistics

Citations

5 citations in Web of Science®
6 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

5 downloads since deposited on 19 Jan 2017
5 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2016
Deposited On:19 Jan 2017 07:32
Last Modified:22 Aug 2017 08:57
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1600-6135
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1111/ajt.13843
PubMed ID:27129409

Download

Download PDF  'Machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines'.
Preview
Content: Published Version
Filetype: PDF
Size: 234kB
View at publisher
Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)