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Sauerstoffhomöostase in Gewebe und Zelle: Wie Sauerstoffmangel die Genexpression reguliert.


Wenger, R H (2004). Sauerstoffhomöostase in Gewebe und Zelle: Wie Sauerstoffmangel die Genexpression reguliert. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie, 39(S1):S38-S43.

Abstract

Every cell of the body is capable of measuring the environmental oxygen concentration. When oxygen supply falls below oxygen demand of the cell (hypoxia), a series of genes will be activated whose products help the cell, the tissue as well as the whole organism in adapting to these altered oxygen concentrations. The discovery of hypoxia-inducible transcription factors (HIFs) allowed the molecular understanding of these processes.

Abstract

Every cell of the body is capable of measuring the environmental oxygen concentration. When oxygen supply falls below oxygen demand of the cell (hypoxia), a series of genes will be activated whose products help the cell, the tissue as well as the whole organism in adapting to these altered oxygen concentrations. The discovery of hypoxia-inducible transcription factors (HIFs) allowed the molecular understanding of these processes.

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Additional indexing

Other titles:[Oxygen homeostasis in tissues and cells: how hypoxia regulates gene expression.]
Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology
Dewey Decimal Classification:570 Life sciences; biology
Language:German
Date:2004
Deposited On:11 Feb 2008 12:22
Last Modified:05 Apr 2016 12:18
Publisher:Thieme
ISSN:0939-2661
Publisher DOI:https://doi.org/10.1055/s-2004-818822
PubMed ID:15490340

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