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Sequential morphometric evaluation at UnicCa(®) and DCD(®) implant surfaces. An experimental study in the dog


Favero, Vittorio; Lang, Niklaus P; Favero, Riccardo; Antunes, Antonio A; Salata, Luiz A; Botticelli, Daniele (2017). Sequential morphometric evaluation at UnicCa(®) and DCD(®) implant surfaces. An experimental study in the dog. Clinical Oral Implants Research, 28(7):833-839.

Abstract

AIM: To study tissue components adjacent to implants with nanotechnologically modified surfaces at different periods of healing.
MATERIAL & METHODS: In 12 beagle dogs, two different implant systems with different surface configurations were randomly installed in the edentulous premolar regions of the mandible. One surface was first acid-etched and subsequently, nanotechnologically modified with calcium ions (UnicCa(®) ), while the other was first sandblasted and acid-etched, and then additionally treated with a nanometer calcium phosphate deposition (discrete crystalline deposition; DCD(®) ). The implants were fully submerged; surgeries and sacrifices were planned to harvest biopsies after 1, 2, 4 and 8 weeks of healing (n = 6 per period). A morphometric evaluation of percentages of new and old bone, bone debris/particles and clot, new soft tissues (provisional matrix and immature marrow), mature bone marrow and vessels was performed in the spongiosa compartment adjacent to the implant surface up to a distance of about 0.4 mm from the surface.
RESULTS: After 2 weeks of healing, the soft tissues were represented by 41.0% at the UnicCa(®) and 37.9% at the DCD(®) surfaces, in both cases mainly being composed of provisional matrix. These percentages decreased over time, being composed of greater amounts of immature bone marrow, and disappeared after 8 weeks. New bone increased progressively between 1 and 8 weeks of healing from 9.7 ± 6.3% to 70.0 ± 8.4% and from 8.2 ± 3.5% to 67.0 ± 6.1% at the UnicCa(®) and DCD(®) surfaces, respectively. Pristine bone was progressively resorbed.
CONCLUSIONS: Throughout the periods of healing observed, the formation of a provisional matrix followed by the formation of new bone and marrow was revealed in a similar fashion as for other modified surface configurations.

Abstract

AIM: To study tissue components adjacent to implants with nanotechnologically modified surfaces at different periods of healing.
MATERIAL & METHODS: In 12 beagle dogs, two different implant systems with different surface configurations were randomly installed in the edentulous premolar regions of the mandible. One surface was first acid-etched and subsequently, nanotechnologically modified with calcium ions (UnicCa(®) ), while the other was first sandblasted and acid-etched, and then additionally treated with a nanometer calcium phosphate deposition (discrete crystalline deposition; DCD(®) ). The implants were fully submerged; surgeries and sacrifices were planned to harvest biopsies after 1, 2, 4 and 8 weeks of healing (n = 6 per period). A morphometric evaluation of percentages of new and old bone, bone debris/particles and clot, new soft tissues (provisional matrix and immature marrow), mature bone marrow and vessels was performed in the spongiosa compartment adjacent to the implant surface up to a distance of about 0.4 mm from the surface.
RESULTS: After 2 weeks of healing, the soft tissues were represented by 41.0% at the UnicCa(®) and 37.9% at the DCD(®) surfaces, in both cases mainly being composed of provisional matrix. These percentages decreased over time, being composed of greater amounts of immature bone marrow, and disappeared after 8 weeks. New bone increased progressively between 1 and 8 weeks of healing from 9.7 ± 6.3% to 70.0 ± 8.4% and from 8.2 ± 3.5% to 67.0 ± 6.1% at the UnicCa(®) and DCD(®) surfaces, respectively. Pristine bone was progressively resorbed.
CONCLUSIONS: Throughout the periods of healing observed, the formation of a provisional matrix followed by the formation of new bone and marrow was revealed in a similar fashion as for other modified surface configurations.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Fixed and Removable Prosthodontics
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2017
Deposited On:08 Dec 2016 15:54
Last Modified:04 Jul 2017 01:00
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0905-7161
Publisher DOI:https://doi.org/10.1111/clr.12888
PubMed ID:27252082

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