Header

UZH-Logo

Maintenance Infos

Sequential morphometric evaluation at UnicCa(®) and SLActive(®) implant surfaces. An experimental study in the dog


Favero, Vittorio; Lang, Niklaus P; Favero, Riccardo; Carneiro Martins Neto, Evandro; Salata, Luiz A; Botticelli, Daniele (2017). Sequential morphometric evaluation at UnicCa(®) and SLActive(®) implant surfaces. An experimental study in the dog. Clinical Oral Implants Research, 28(9):1023-1029.

Abstract

AIM: To study sequential osseointegration around implants with nano-technologically modified surfaces at different periods of healing.
MATERIALS AND METHODS: After 3 months, two different implant systems with different nano-technologically modified surfaces were randomly installed in the edentulous molar regions of the mandible of 12 dogs. One surface was acid-etched surface, and subsequently modified with calcium ions (UnicCa(®) ), while the other was a hydrophilic sandblasted with large grit and acid-etched (SLActive(®) ) surface. The implants were fully submerged, and biopsies were obtained representing the healing after 1, 2, 4 and 8 weeks (n = 6 per period). A morphometric evaluation of densities of new soft tissues (provisional matrix and immature bone marrow), new and old bone, mature bone marrow, vessels and other tissues (bone debris/particles and clot) was performed in the spongiosa compartment of the sites of implantation.
RESULTS: After 1 week of healing, the soft tissues, mainly composed of provisional matrix, were present at 41.5 ± 23.9% and 30.1 ± 20.0% at the UnicCa(®) and SLActive surfaces, respectively. These percentages were >40% at both surfaces after 2 weeks of healing, presenting greater amount of immature bone marrow. Subsequently, these percentages decreased up to disappear after 8 weeks of healing. New bone increased progressively between 1 and 8 weeks of healing from 8.2 ± 3.0% to 77.1 ± 6.4% and from 6.8 ± 2.8% to 67.9 ± 6.8% at the UnicCa(®) and SLActive(®) , respectively. Old bone decreased progressively over time.
CONCLUSIONS: The patterns of healing at highly hydrophilic surfaces occurred through the early formation of a provisional matrix followed by the formation of new bone and marrow at various stages of maturation. The healing was similar to those described in different animal models, anatomical sites and surgical procedures.

Abstract

AIM: To study sequential osseointegration around implants with nano-technologically modified surfaces at different periods of healing.
MATERIALS AND METHODS: After 3 months, two different implant systems with different nano-technologically modified surfaces were randomly installed in the edentulous molar regions of the mandible of 12 dogs. One surface was acid-etched surface, and subsequently modified with calcium ions (UnicCa(®) ), while the other was a hydrophilic sandblasted with large grit and acid-etched (SLActive(®) ) surface. The implants were fully submerged, and biopsies were obtained representing the healing after 1, 2, 4 and 8 weeks (n = 6 per period). A morphometric evaluation of densities of new soft tissues (provisional matrix and immature bone marrow), new and old bone, mature bone marrow, vessels and other tissues (bone debris/particles and clot) was performed in the spongiosa compartment of the sites of implantation.
RESULTS: After 1 week of healing, the soft tissues, mainly composed of provisional matrix, were present at 41.5 ± 23.9% and 30.1 ± 20.0% at the UnicCa(®) and SLActive surfaces, respectively. These percentages were >40% at both surfaces after 2 weeks of healing, presenting greater amount of immature bone marrow. Subsequently, these percentages decreased up to disappear after 8 weeks of healing. New bone increased progressively between 1 and 8 weeks of healing from 8.2 ± 3.0% to 77.1 ± 6.4% and from 6.8 ± 2.8% to 67.9 ± 6.8% at the UnicCa(®) and SLActive(®) , respectively. Old bone decreased progressively over time.
CONCLUSIONS: The patterns of healing at highly hydrophilic surfaces occurred through the early formation of a provisional matrix followed by the formation of new bone and marrow at various stages of maturation. The healing was similar to those described in different animal models, anatomical sites and surgical procedures.

Statistics

Altmetrics

Downloads

1 download since deposited on 08 Dec 2016
1 download since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Fixed and Removable Prosthodontics
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2017
Deposited On:08 Dec 2016 15:35
Last Modified:23 Sep 2017 21:33
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0905-7161
Publisher DOI:https://doi.org/10.1111/clr.12906
PubMed ID:27302198

Download

Preview Icon on Download
Content: Published Version
Filetype: PDF - Registered users only
Size: 2MB
View at publisher