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Children and adolescents show altered visual working memory related brain activity more than one decade after arterial switch operation for d-transposition of the great arteries


Klaver, Peter; Knirsch, Walter; Wurmitzer, Karoline; von Allmen, David Yoh (2016). Children and adolescents show altered visual working memory related brain activity more than one decade after arterial switch operation for d-transposition of the great arteries. Developmental Neuropsychology, 41(4):261-267.

Abstract

This pilot study investigated neural correlates of visual working memory using functional magnetic resonance imaging (fMRI) in seven patients more than one decade after neonatal arterial switch operation for surgical correction of d-transposition of the great arteries (d-TGA, aged 10-18 years, 1 female). Compared with age and sex matched healthy controls patients showed similar visual working memory performance and a smaller increase in brain activity in the posterior parietal cortex with higher visual working memory load. These findings suggest that patients exhibit altered neural activity within a network that is known to support visuospatial memory and cognition.

Abstract

This pilot study investigated neural correlates of visual working memory using functional magnetic resonance imaging (fMRI) in seven patients more than one decade after neonatal arterial switch operation for surgical correction of d-transposition of the great arteries (d-TGA, aged 10-18 years, 1 female). Compared with age and sex matched healthy controls patients showed similar visual working memory performance and a smaller increase in brain activity in the posterior parietal cortex with higher visual working memory load. These findings suggest that patients exhibit altered neural activity within a network that is known to support visuospatial memory and cognition.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:December 2016
Deposited On:24 Jan 2017 09:45
Last Modified:29 Jan 2017 06:48
Publisher:Taylor & Francis
ISSN:1532-6942
Additional Information:This is an Accepted Manuscript of an article published by Taylor & Francis in Developmental Neuropsychology on 5 Dec 2016, available online: http://wwww.tandfonline.com/10.1080/87565641.2016.1243115.
Publisher DOI:https://doi.org/10.1080/87565641.2016.1243115
PubMed ID:27918206

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