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Shigella antimicrobial drug resistance mechanisms, 2004–2014


Nüesch-Inderbinen, Magdalena; Heini, Nicole; Zurfluh, Katrin; Althaus, Denise; Hächler, Herbert; Stephan, Roger (2016). Shigella antimicrobial drug resistance mechanisms, 2004–2014. Emerging Infectious Diseases, 22(6):1083-1085.

Abstract

To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004–2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced susceptibility to azithromycin, a last-resort antimicrobial agent for shigellosis.

Abstract

To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004–2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced susceptibility to azithromycin, a last-resort antimicrobial agent for shigellosis.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Food Safety and Hygiene
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Uncontrolled Keywords:Shigella; antimicrobial resistance; antimicrobial treatment; azithromycin; bacteria; cephalosporins; ciprofloxacin; multidrug resistance; resistance genes
Language:English
Date:2016
Deposited On:17 Jan 2017 10:55
Last Modified:02 Feb 2018 11:13
Publisher:U.S. National Center for Infectious Diseases
ISSN:1080-6040
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.3201/eid2206.152088
PubMed ID:27191035

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