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Condylar resorption in orthognathic patients after mandibular bilateral sagittal split osteotomy: a systematic review


Mousoulea, Sophia; Kloukos, Dimitrios; Sampaziotis, Dimitrios; Vogiatzi, Theodosia; Eliades, Theodore (2017). Condylar resorption in orthognathic patients after mandibular bilateral sagittal split osteotomy: a systematic review. European Journal of Orthodontics, 39(3):294-309.

Abstract

OBJECTIVE: To systematically search the literature and assess the available evidence regarding the incidence and quantification of condylar resorption following bilateral sagittal split osteotomy (BSSO) of the mandible in orthognathic patients.
SEARCH METHODS: Electronic database searches of published and unpublished literature were performed. The reference lists of eligible studies were hand searched for additional studies.
SELECTION CRITERIA: Randomized clinical trials (RCTs), prospective, and retrospective studies with patients of any age that underwent BSSO were included.
DATA COLLECTION AND ANALYSIS: Study selection, data extraction, and risk of bias assessment were performed individually and in duplicate.
RESULTS: One RCT, 3 prospective, and 10 retrospective studies were included in this review. The lack of standardized protocols and the high amount of heterogeneity precluded a valid interpretation of the actual results through pooled estimates. There was a substantial consistency among studies, however, that young, female patients with mandibular deficiency and high mandibular plane angle, submitted to surgical counterclockwise rotation of mandibular segments, were more prone to a higher risk for condylar resorption after BSSO. The level of evidence was found to be low given the high/serious risk of bias in all included studies.
CONCLUSIONS: Condylar resorption should be taken into account as a potential postsurgical complication after BSSO. However, its incidence and quantification need precautious interpretation owing to the low level of evidence and the high heterogeneity of studies. Additional high-quality prospective research assisted by 3D imaging technology is needed to allow more definitive conclusions.
REGISTRATION: Study not registered.
CONFLICT OF INTEREST: None.

Abstract

OBJECTIVE: To systematically search the literature and assess the available evidence regarding the incidence and quantification of condylar resorption following bilateral sagittal split osteotomy (BSSO) of the mandible in orthognathic patients.
SEARCH METHODS: Electronic database searches of published and unpublished literature were performed. The reference lists of eligible studies were hand searched for additional studies.
SELECTION CRITERIA: Randomized clinical trials (RCTs), prospective, and retrospective studies with patients of any age that underwent BSSO were included.
DATA COLLECTION AND ANALYSIS: Study selection, data extraction, and risk of bias assessment were performed individually and in duplicate.
RESULTS: One RCT, 3 prospective, and 10 retrospective studies were included in this review. The lack of standardized protocols and the high amount of heterogeneity precluded a valid interpretation of the actual results through pooled estimates. There was a substantial consistency among studies, however, that young, female patients with mandibular deficiency and high mandibular plane angle, submitted to surgical counterclockwise rotation of mandibular segments, were more prone to a higher risk for condylar resorption after BSSO. The level of evidence was found to be low given the high/serious risk of bias in all included studies.
CONCLUSIONS: Condylar resorption should be taken into account as a potential postsurgical complication after BSSO. However, its incidence and quantification need precautious interpretation owing to the low level of evidence and the high heterogeneity of studies. Additional high-quality prospective research assisted by 3D imaging technology is needed to allow more definitive conclusions.
REGISTRATION: Study not registered.
CONFLICT OF INTEREST: None.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Orthodontics and Pediatric Dentistry
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 June 2017
Deposited On:01 Feb 2017 17:02
Last Modified:22 Sep 2017 16:17
Publisher:Oxford University Press
ISSN:0141-5387
Additional Information:This is a pre-copy-editing, author-produced PDF of an article accepted for publication in The European Journal of Orthodontics following peer review. The definitive publisher-authenticated version is available online at:https://academic.oup.com/ejo/article-lookup/doi/10.1093/ejo/cjw045
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/ejo/cjw045
PubMed ID:27334905

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