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Experts opinion on the practical use of azathioprine and 6-mercaptopurine in inflammatory bowel disease


Mottet, Christian; Schoepfer, Alain M; Juillerat, Pascal; Cosnes, Jacques; Froehlich, Florian; Kessler-Brondolo, Vera; Seibold, Frank; Rogler, Gerhard; Vavricka, Stephan R; Michetti, Pierre (2016). Experts opinion on the practical use of azathioprine and 6-mercaptopurine in inflammatory bowel disease. Inflammatory Bowel Diseases, 22(11):2733-2747.

Abstract

The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications. In this article, a panel of experts gives advice, based on the relevant literature, on indications and practical use of azathioprine/6-mercaptopurine, prevention, and management of drug adverse reactions and special situations such as vaccination, pregnancy, and lactation.

Abstract

The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications. In this article, a panel of experts gives advice, based on the relevant literature, on indications and practical use of azathioprine/6-mercaptopurine, prevention, and management of drug adverse reactions and special situations such as vaccination, pregnancy, and lactation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Gastroenterology and Hepatology
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:November 2016
Deposited On:13 Feb 2017 13:55
Last Modified:02 Feb 2018 12:09
Publisher:Lippincott Williams & Wilkins
ISSN:1078-0998
OA Status:Hybrid
Publisher DOI:https://doi.org/10.1097/MIB.0000000000000923
PubMed ID:27760078

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