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Takayasu's arteritis with isolated pulmonary artery involvement in a middle-aged asian woman with Hepatitis B and latent tuberculosis infection


Liebscher, Felix; Pfammatter, Thomas; Kolios, Antonios; Greutmann, Matthias; Franzen, Daniel (2017). Takayasu's arteritis with isolated pulmonary artery involvement in a middle-aged asian woman with Hepatitis B and latent tuberculosis infection. Respiration, 93(3):207-211.

Abstract

We report a rare case of Takayasu's arteritis with isolated pulmonary artery stenosis in the presence of active hepatitis B and latent Mycobacterium tuberculosis infection in a middle-aged Asian woman who initially presented with severe dyspnea on exertion and recurrent syncope, occasional burning chest pains, and fatigue. Therapy of the active hepatitis B and latent M. tuberculosis infection together with a course of methotrexate led to a slight reversal of the symptoms, as angioplasty with or without stenting was not an option. The constellation described here hints at the possible link between hepatitis B and M. tuberculosis infection and the development of Takayasu's arteritis. The case also supports the little evidence available indicating that treatment of active hepatitis B infection could positively influence the course of Takayasu's arteritis.

Abstract

We report a rare case of Takayasu's arteritis with isolated pulmonary artery stenosis in the presence of active hepatitis B and latent Mycobacterium tuberculosis infection in a middle-aged Asian woman who initially presented with severe dyspnea on exertion and recurrent syncope, occasional burning chest pains, and fatigue. Therapy of the active hepatitis B and latent M. tuberculosis infection together with a course of methotrexate led to a slight reversal of the symptoms, as angioplasty with or without stenting was not an option. The constellation described here hints at the possible link between hepatitis B and M. tuberculosis infection and the development of Takayasu's arteritis. The case also supports the little evidence available indicating that treatment of active hepatitis B infection could positively influence the course of Takayasu's arteritis.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:21 January 2017
Deposited On:16 Feb 2017 09:48
Last Modified:08 Dec 2017 23:36
Publisher:Karger
ISSN:0025-7931
Publisher DOI:https://doi.org/10.1159/000454955
PubMed ID:28110338

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