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Embolization of Juvenile Angiofibromas


Valavanis, Anton; Baltsavias, Gerasimos (2017). Embolization of Juvenile Angiofibromas. In: Dubey, Siba P; Schick, Bernhard. Juvenile Angiofibroma. Zürich, Switzerland: Springer International Publishing, 99-116.

Abstract

Embolization is recognized as an established endovascular interventional neuroradiologic technique for the preoperative devascularization of juvenile angiofibromas. The goal of preoperative embolization of juvenile angiofibromas is the selective obliteration of the intratumoral abnormal arteriolocapillary bed, leading to tumor devascularization, with preservation of the normal arterial supply to surrounding tissues followed by ischemic transformation and some size reduction of the tumor. These embolization-induced changes improve the surgical conditions and contribute to radical tumor removal with minimal intraoperative blood loss. Appropriately performed embolization based on detailed knowledge of the local functional vascular anatomy carries a minimal risk for permanent neurologic morbidity and no mortality. To achieve this goal, a thorough pretherapeutic tumor evaluation by imaging techniques, a detailed angiographic workup, and the application of appropriate embolization techniques, which are described in detail, are necessary.

Abstract

Embolization is recognized as an established endovascular interventional neuroradiologic technique for the preoperative devascularization of juvenile angiofibromas. The goal of preoperative embolization of juvenile angiofibromas is the selective obliteration of the intratumoral abnormal arteriolocapillary bed, leading to tumor devascularization, with preservation of the normal arterial supply to surrounding tissues followed by ischemic transformation and some size reduction of the tumor. These embolization-induced changes improve the surgical conditions and contribute to radical tumor removal with minimal intraoperative blood loss. Appropriately performed embolization based on detailed knowledge of the local functional vascular anatomy carries a minimal risk for permanent neurologic morbidity and no mortality. To achieve this goal, a thorough pretherapeutic tumor evaluation by imaging techniques, a detailed angiographic workup, and the application of appropriate embolization techniques, which are described in detail, are necessary.

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Item Type:Book Section, not refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neuroradiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2017
Deposited On:21 Feb 2017 08:10
Last Modified:21 Feb 2017 08:12
Publisher:Springer International Publishing
ISBN:978-3-319-45341-5
Publisher DOI:https://doi.org/10.1007/978-3-319-45343-9_9
Related URLs:https://doi.org/10.1007/978-3-319-45343-9 (Publisher)

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