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Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis


Khanna, Dinesh; Furst, Daniel E; Clements, Philip J; Allanore, Yannick; Baron, Murray; Czirjak, Lazlo; Distler, Oliver; Foeldvari, Ivan; Kuwana, Masataka; Matucci-Cerinic, Marco; Mayes, Maureen; Medsger, Thomas; Merkel, Peter A; Pope, Janet E; Seibold, James R; Steen, Virginia; Stevens, Wendy; Denton, Christopher P (2017). Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis. Journal of scleroderma and related disorders, 2(1):11-18.

Abstract

The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.

Abstract

The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Rheumatology Clinic and Institute of Physical Medicine
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2017
Deposited On:30 May 2017 14:18
Last Modified:03 Aug 2017 20:40
Publisher:Wichtig Publishing
ISSN:2397-1983
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.5301/jsrd.5000231
PubMed ID:28516167

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