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Anaesthesia recovery quality after racemic ketamine or S-ketamine administration to male cats undergoing neutering surgery


Larenza, M P; Althaus, H; Conrot, A; Schatzmann, U; Bettschart-Wolfensberger, Regula (2008). Anaesthesia recovery quality after racemic ketamine or S-ketamine administration to male cats undergoing neutering surgery. Schweizer Archiv für Tierheilkunde, 150(12):599-607.

Abstract

Postoperative anasthesia recovery and analgesia qualities were compared in cats anaesthetised with racemic ketamine (RS-ket) or S-ketamine (S-ket) undergoing orchiectomy.
Twenty client-owned male cats received medetomidine (0.03 mg/kg) and S-ket (6 mg/kg; n=10) or RS-ket (10 mg/kg; n=10), all intramuscularly. After routine orchiectomy, animals received atipamezole (0.15 mg/kg) intramuscularly. Thirty and 60 min after atipamezole administration, one observer unaware of the treatment identity evaluated analgesia using a visual analogue scale (VAS) and, my means of four points scales, sedation, unprovoked behaviour and behavioural reaction to external stimuli. Cats with a VAS > 15 mm were to receive butorphanol. Times to sternal and standing positions were recorded. After 60 min, cats were given carprofen (4 mg/kg) subcutaneously. Anaesthesia with S-ket, at 60 % of the RS-ket dose, provided faster recoveries. At 60 min, undisturbed cats in S-ket group had a trend towards fewer behavioural changes. Cats in RS-ket group were more sedate at 30 min and responded with a lower intensity to external stimulation. Immediate postoperative analgesia was considered adequate for both groups and no cat required butorphanol administration.

Abstract

Postoperative anasthesia recovery and analgesia qualities were compared in cats anaesthetised with racemic ketamine (RS-ket) or S-ketamine (S-ket) undergoing orchiectomy.
Twenty client-owned male cats received medetomidine (0.03 mg/kg) and S-ket (6 mg/kg; n=10) or RS-ket (10 mg/kg; n=10), all intramuscularly. After routine orchiectomy, animals received atipamezole (0.15 mg/kg) intramuscularly. Thirty and 60 min after atipamezole administration, one observer unaware of the treatment identity evaluated analgesia using a visual analogue scale (VAS) and, my means of four points scales, sedation, unprovoked behaviour and behavioural reaction to external stimuli. Cats with a VAS > 15 mm were to receive butorphanol. Times to sternal and standing positions were recorded. After 60 min, cats were given carprofen (4 mg/kg) subcutaneously. Anaesthesia with S-ket, at 60 % of the RS-ket dose, provided faster recoveries. At 60 min, undisturbed cats in S-ket group had a trend towards fewer behavioural changes. Cats in RS-ket group were more sedate at 30 min and responded with a lower intensity to external stimulation. Immediate postoperative analgesia was considered adequate for both groups and no cat required butorphanol administration.

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Additional indexing

Other titles:Postoperative Aufwachphase und Analgesie nach der Kastration von männlichen Katzen unter Anästhesie mit Ketamin Razemat oder S-Ketamin
Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:December 2008
Deposited On:18 Feb 2009 15:17
Last Modified:04 Jun 2016 07:15
Publisher:Hans Huber
ISSN:0036-7281
Publisher DOI:https://doi.org/10.1024/0036-7281.150.12.599
PubMed ID:19034844

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