Header

UZH-Logo

Maintenance Infos

Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model


Buschmann, Johanna; Balli, Eleni; Hess, Samuel C; Stark, Wendelin J; Cinelli, Paolo; Märsmann, Sonja; Welti, Manfred; Weder, Walter; Jungraithmayr, Wolfgang (2017). Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model. Injury, 48(10):2080-2088.

Abstract

OBJECTIVES Malignant neoplasms infiltrating the chest wall often requires resection of the thoracic wall. To replace the defect, Gore-Tex(®) is usually employed as the gold standard material, however, Gore-Tex(®) is inert and not degradable. Novel materials are nowadays available which allow a full bio-integration due to their non-toxic degradability. Additionally, stem cell seeding has the capacity to reduce inflammatory response towards such grafts, thus integrating it better into the host organism.

Abstract

OBJECTIVES Malignant neoplasms infiltrating the chest wall often requires resection of the thoracic wall. To replace the defect, Gore-Tex(®) is usually employed as the gold standard material, however, Gore-Tex(®) is inert and not degradable. Novel materials are nowadays available which allow a full bio-integration due to their non-toxic degradability. Additionally, stem cell seeding has the capacity to reduce inflammatory response towards such grafts, thus integrating it better into the host organism.

Statistics

Altmetrics

Downloads

0 downloads since deposited on 22 Sep 2017
0 downloads since 12 months

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Department of Trauma Surgery
04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:4 August 2017
Deposited On:22 Sep 2017 08:17
Last Modified:09 Dec 2017 02:19
Publisher:Elsevier
ISSN:0020-1383
Publisher DOI:https://doi.org/10.1016/j.injury.2017.08.004
PubMed ID:28842288

Download