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Comparison of pyoderma gangrenosum and hypertensive ischemic leg ulcer Martorell in a Swiss cohort


Kolios, Antonios G A; Hafner, Jürg; Luder, C; Guenova, Emmanuella; Kerl, K; Kempf, Werner; Nilsson, J; French, L E; Cozzio, A (2017). Comparison of pyoderma gangrenosum and hypertensive ischemic leg ulcer Martorell in a Swiss cohort. British Journal of Dermatology:Epub ahead of print.

Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis presenting with painful and sterile skin ulcerations (1). Its aetiology remains largely unknown although an autoinflammatory background seems possible. Several comorbidities as well as triggering factors such as surgery, trauma or pharmacological therapies have been associated with the development of PG (2). Different topical and systemic treatments are recommended for PG, most commonly topical steroids or calcineurin inhibitors as well as systemic steroids, dapsone, infliximab and others, as well as by our group and others canakinumab and ustekinumab (3, 4). This article is protected by copyright. All rights reserved.

Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis presenting with painful and sterile skin ulcerations (1). Its aetiology remains largely unknown although an autoinflammatory background seems possible. Several comorbidities as well as triggering factors such as surgery, trauma or pharmacological therapies have been associated with the development of PG (2). Different topical and systemic treatments are recommended for PG, most commonly topical steroids or calcineurin inhibitors as well as systemic steroids, dapsone, infliximab and others, as well as by our group and others canakinumab and ustekinumab (3, 4). This article is protected by copyright. All rights reserved.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Immunology
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:CRP ; Pyoderma gangrenosum; hypertensive ischemic leg ulcer Martorell; neutrophilia; systemic inflammation
Language:English
Date:20 August 2017
Deposited On:10 Oct 2017 14:57
Last Modified:09 Dec 2017 02:40
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0007-0963
Publisher DOI:https://doi.org/10.1111/bjd.15901
PubMed ID:28832960

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Language: English
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Embargo till: 2018-08-20