Header

UZH-Logo

Maintenance Infos

Synovial fibroblasts in 2017


Ospelt, Caroline (2017). Synovial fibroblasts in 2017. RMD Open, 3(2):e000471.

Abstract

Stromal cells like synovial fibroblasts gained great interest over the years, since it has become clear that they strongly influence their environment and neighbouring cells. The current review describes the role of synovial fibroblasts as cells of the innate immune system and expands on their involvement in inflammation and cartilage destruction in rheumatoid arthritis (RA). Furthermore, epigenetic changes in RA synovial fibroblasts and studies that focused on the identification of different subsets of synovial fibroblasts are discussed.

Abstract

Stromal cells like synovial fibroblasts gained great interest over the years, since it has become clear that they strongly influence their environment and neighbouring cells. The current review describes the role of synovial fibroblasts as cells of the innate immune system and expands on their involvement in inflammation and cartilage destruction in rheumatoid arthritis (RA). Furthermore, epigenetic changes in RA synovial fibroblasts and studies that focused on the identification of different subsets of synovial fibroblasts are discussed.

Statistics

Altmetrics

Downloads

1 download since deposited on 21 Nov 2017
1 download since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Rheumatology Clinic and Institute of Physical Medicine
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2017
Deposited On:21 Nov 2017 16:31
Last Modified:09 Dec 2017 03:39
Publisher:BMJ Publishing Group
ISSN:2056-5933
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1136/rmdopen-2017-000471
PubMed ID:29081987

Download

Download PDF  'Synovial fibroblasts in 2017'.
Preview
Content: Published Version
Filetype: PDF
Size: 862kB
View at publisher
Licence: Creative Commons: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)