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Outcomes in degenerative mitral regurgitation: current state-of-the art and future directions


Desai, Milind Y; Grigioni, Francesco; Di Eusanio, Marco; Saccocci, Matteo; Taramasso, Maurizio; Maisano, Francesco; Suri, Rakesh M; Gillinov, A Marc (2017). Outcomes in degenerative mitral regurgitation: current state-of-the art and future directions. Progress in Cardiovascular Diseases, 60(3):370-385.

Abstract

Mitral regurgitation (MR) is the one of the most frequent valvular heart diseases in the developed world, often requiring surgical correction. Degenerative MR is the most common type of non-ischemic, organic MR in the western world. Since no medical treatment has been shown to be effective in preventing the consequences of volume overload in asymptomatic degenerative MR, risk stratification is essential. Currently, this is achieved using clinical and precisely quantified echocardiographic parameters, with newer technologies like cardiac magnetic resonance gaining increasing prominence. While surgical mitral repair, often performed using minimally invasive/robotic techniques, is the current gold-standard for definitive therapeutic management, there is rapid emergence of percutaneous techniques for mitral valve repair/replacement in cases of degenerative MR. This state-of-the-art-review will discuss the latest knowledge in the natural history, imaging, surgical and percutaneous therapies in patients with degenerative MR.

Abstract

Mitral regurgitation (MR) is the one of the most frequent valvular heart diseases in the developed world, often requiring surgical correction. Degenerative MR is the most common type of non-ischemic, organic MR in the western world. Since no medical treatment has been shown to be effective in preventing the consequences of volume overload in asymptomatic degenerative MR, risk stratification is essential. Currently, this is achieved using clinical and precisely quantified echocardiographic parameters, with newer technologies like cardiac magnetic resonance gaining increasing prominence. While surgical mitral repair, often performed using minimally invasive/robotic techniques, is the current gold-standard for definitive therapeutic management, there is rapid emergence of percutaneous techniques for mitral valve repair/replacement in cases of degenerative MR. This state-of-the-art-review will discuss the latest knowledge in the natural history, imaging, surgical and percutaneous therapies in patients with degenerative MR.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Degenerative mitral regurgitation, Minimally invasive mitral surgery, Outcomes, Transcatheter mitral valve therapies
Language:English
Date:9 November 2017
Deposited On:01 Dec 2017 17:44
Last Modified:19 Feb 2018 09:27
Publisher:Elsevier
ISSN:0033-0620
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.pcad.2017.10.005
PubMed ID:29128570

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