To avoid infections and wound healing disorders Triclosan coated sutures have been invented. Little is known of these sutures regarding their tensile properties. Three different Triclosan coated sutures (Vicryl 1 plus, PDS 0 plus, Monocryl 3-0 plus) were tested at several time points over 42 days regarding load to failure, strain and stiffness compared to their non-coated versions (Vicryl 1, PDS 0, Monocryl 3-0). Four different measurement points were made. Suture loops were fixed in a material testing machine over two metal bars which were moved apart creating a stress to the fiber. Unpaired, two-tailed t-test were performed for each group (untreated and treated) while level of significance was defined at a level of P<0.05. Vicryl 1 was significantly stronger on day 14 than Vicryl 1 plus (p=0.033). On day 28 significant changes were found in PDS 0 which was weaker compared to PDS 0 plus (p=0.039) and Vicryl 1 which was stronger than Vicryl 1 plus (p=0.032). We have seen that Vicryl 1 plus sutures are significantly weaker according to loading to failure after 14 and 28 days, which might cause incisional hernias. PDS 0 sutures are used to reconstruct tendons, therefore a longer durableness might be of interest as re-ruptures of tendons are problematic. Our in vitro findings support the use of Triclosan coated PDS plus sutures and Vicryl sutures as they show a longer resistance. This article is protected by copyright. All rights reserved.