The aim of this retrospective study was to document secondary wound healing and outcome in 20 cattle that had undergone digit amputation at the level of the distal metaphysis of the first phalanx between April 2009 and June 2015. The surgical technique for amputation was simple and fast, and granulation tissue covered the stump of the first phalanx 9 to 30 days postoperatively. Complications associated with wound healing were seen in 7 animals and in 3, a second surgery was required; all 20 cattle were discharged from the clinic. Epithelial closure was complete after a mean of 3 months (range, 2 to 7 months). The mean postoperative survival time was 15 months (range, 1 to 34 months), and 6 animals were still alive at the time of follow-up inquiry. Wound healing and long-term outcome did not differ between cattle that had undergone a more intensive aftercare regime than those with a less intensive postoperative treatment.