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Paternal experience impacts cognitive function in offspring: a pre-existing concept


Bohacek, J; Weber-Stadlbauer, U; Mansuy, I M (2017). Paternal experience impacts cognitive function in offspring: a pre-existing concept. Molecular Psychiatry:Epub ahead of print.

Abstract

The field of epigenetics has gained major importance over the past decade and led to the emergence of new conceptual thinking in biology and medicine. One of the most fascinating of these new ideas is the concept of germline epigenetic inheritance, which suggests that environmental factors can induce epigenetic alterations in germ cells, which can influence offspring. Recent scientific breakthroughs have provided causal evidence for germline epigenetic inheritance in mammals. Over the last couple of years, the field has exponentially grown, and evidence to suggest that a wide range of environmental factors can induce heritable changes is rapidly accumulating. Although still very novel, new studies need to consider this prior knowledge if the field is to move forward efficiently.

Abstract

The field of epigenetics has gained major importance over the past decade and led to the emergence of new conceptual thinking in biology and medicine. One of the most fascinating of these new ideas is the concept of germline epigenetic inheritance, which suggests that environmental factors can induce epigenetic alterations in germ cells, which can influence offspring. Recent scientific breakthroughs have provided causal evidence for germline epigenetic inheritance in mammals. Over the last couple of years, the field has exponentially grown, and evidence to suggest that a wide range of environmental factors can induce heritable changes is rapidly accumulating. Although still very novel, new studies need to consider this prior knowledge if the field is to move forward efficiently.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
07 Faculty of Science > Institute of Pharmacology and Toxicology

04 Faculty of Medicine > Neuroscience Center Zurich
05 Vetsuisse Faculty > Institute of Veterinary Pharmacology and Toxicology
04 Faculty of Medicine > Brain Research Institute
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:July 2017
Deposited On:09 Jan 2018 15:32
Last Modified:19 Feb 2018 10:05
Publisher:Nature Publishing Group
ISSN:1359-4184
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1038/mp.2017.162
PubMed ID:29155798

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