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Coronary risk assessment at X-ray dose equivalent ungated chest CT: Results of a multi-reader study


Messerli, Michael; Hechelhammer, Lukas; Leschka, Sebastian; Warschkow, René; Wildermuth, Simon; Bauer, Ralf W (2018). Coronary risk assessment at X-ray dose equivalent ungated chest CT: Results of a multi-reader study. Clinical Imaging, 49:73-79.

Abstract

OBJECTIVES: To determine the value of ultra-low dose chest CT with tin filtration for ordinal coronary artery calcium (CAC) risk scoring.
METHODS: 50 patients were prospectively included and underwent clinical standard dose chest CT (1.8±0.7mSv) and ultra-low dose CT (0.13±0.01mSv). Four radiologists estimated presence and extent of CAC.
RESULTS: Weighted kappa values for CAC were 0.76-0.97 in standard dose and 0.75-0.95 in ultra-low dose CT (p<0.001). Good to excellent agreement was observed for CAC ordinal risk assessment, with readers reporting identical risk in 81% of cases.
CONCLUSION: CAC risk can be qualitatively assessed from X-ray dose equivalent ungated chest CT.

Abstract

OBJECTIVES: To determine the value of ultra-low dose chest CT with tin filtration for ordinal coronary artery calcium (CAC) risk scoring.
METHODS: 50 patients were prospectively included and underwent clinical standard dose chest CT (1.8±0.7mSv) and ultra-low dose CT (0.13±0.01mSv). Four radiologists estimated presence and extent of CAC.
RESULTS: Weighted kappa values for CAC were 0.76-0.97 in standard dose and 0.75-0.95 in ultra-low dose CT (p<0.001). Good to excellent agreement was observed for CAC ordinal risk assessment, with readers reporting identical risk in 81% of cases.
CONCLUSION: CAC risk can be qualitatively assessed from X-ray dose equivalent ungated chest CT.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Radiology Nuclear Medicine and imaging
Language:English
Date:25 October 2018
Deposited On:08 Feb 2018 20:11
Last Modified:19 Aug 2018 13:55
Publisher:Elsevier
ISSN:0899-7071
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.clinimag.2017.10.014
PubMed ID:29149718

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