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Atrial myxomas and thrombi: comparison of imaging features on CT


Scheffel, H; Baumueller, S; Stolzmann, P; Leschka, S; Plass, A; Alkadhi, H; Schertler, T (2009). Atrial myxomas and thrombi: comparison of imaging features on CT. American Journal of Roentgenology, 192(3):639-645.

Abstract

OBJECTIVE: The purpose of our study was to compare the imaging features of atrial myxomas and thrombi using CT and to assess the accuracy of CT for determining the origin of myxomas in comparison with surgical findings. MATERIALS AND METHODS: From July 2006 until June 2008, 23 patients (15 women, eight men; mean age, 63 +/- 14 years) with atrial myxomas (n = 13) and thrombi (n = 11) who underwent dual-source CT coronary angiography were included in this retrospective study. Two independent and blinded readers evaluated quantitative (CT attenuation and size) and qualitative (location, origin, shape, mobility, prolapse, and calcifications) parameters at CT. The shape and origin of myxomas were compared with the findings at surgery. RESULTS: No significant differences regarding the CT attenuation of myxomas in comparison with thrombi were found (43 +/- 14 HU vs 57 +/- 30 HU; p = 0.23). Myxomas were significantly larger than thrombi (33 +/- 16 mm vs 21 +/- 7 mm; p < 0.05). The lesions were found equally in the left and right atria (p = 0.11). The origin (p < 0.001), shape (p < 0.05), mobility (p < 0.01), and occurrence of prolapse (p < 0.01) differed significantly between the lesions. Calcifications did not differ between the lesions (p = 0.2). In comparison with surgery, the origin of myxomas was correctly evaluated by CT in 11 of 13 patients (fossa ovalis, n = 5; interatrial septum, n = 4; and lateral atrial wall, n = 2), whereas CT misclassified the origin of two myxomas (posterior and lateral wall left atria at CT vs fossa ovalis at surgery). CONCLUSION: Atrial myxomas and thrombi can be differentiated by their distinguishing features of size, origin, shape, mobility, and prolapse. CT is accurate in determining the origin of myxomas but may fail in some cases.

Abstract

OBJECTIVE: The purpose of our study was to compare the imaging features of atrial myxomas and thrombi using CT and to assess the accuracy of CT for determining the origin of myxomas in comparison with surgical findings. MATERIALS AND METHODS: From July 2006 until June 2008, 23 patients (15 women, eight men; mean age, 63 +/- 14 years) with atrial myxomas (n = 13) and thrombi (n = 11) who underwent dual-source CT coronary angiography were included in this retrospective study. Two independent and blinded readers evaluated quantitative (CT attenuation and size) and qualitative (location, origin, shape, mobility, prolapse, and calcifications) parameters at CT. The shape and origin of myxomas were compared with the findings at surgery. RESULTS: No significant differences regarding the CT attenuation of myxomas in comparison with thrombi were found (43 +/- 14 HU vs 57 +/- 30 HU; p = 0.23). Myxomas were significantly larger than thrombi (33 +/- 16 mm vs 21 +/- 7 mm; p < 0.05). The lesions were found equally in the left and right atria (p = 0.11). The origin (p < 0.001), shape (p < 0.05), mobility (p < 0.01), and occurrence of prolapse (p < 0.01) differed significantly between the lesions. Calcifications did not differ between the lesions (p = 0.2). In comparison with surgery, the origin of myxomas was correctly evaluated by CT in 11 of 13 patients (fossa ovalis, n = 5; interatrial septum, n = 4; and lateral atrial wall, n = 2), whereas CT misclassified the origin of two myxomas (posterior and lateral wall left atria at CT vs fossa ovalis at surgery). CONCLUSION: Atrial myxomas and thrombi can be differentiated by their distinguishing features of size, origin, shape, mobility, and prolapse. CT is accurate in determining the origin of myxomas but may fail in some cases.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2009
Deposited On:12 Mar 2009 09:59
Last Modified:12 Sep 2016 12:02
Publisher:American Roentgen Ray Society
ISSN:0361-803X
Publisher DOI:https://doi.org/10.2214/AJR.08.1694
PubMed ID:19234259

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