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Neural adaptation and the ECAP response threshold: a pilot study


Lai, W K; Dillier, N (2009). Neural adaptation and the ECAP response threshold: a pilot study. Cochlear Implants International, 10(Suppl ):63-67.

Abstract

The electrically evoked compound action potential (ECAP) amplitude resulting from a train of pulses of finite duration (100 ms or 200 ms) was found to vary inversely to the stimulation rate (pulse rate), corroborating well with neural adaptation results from a previous study (Dillier et al., 2005). Amplitude growth functions based on these adapted responses yield thresholds (TNRT) that increase with increasing pulse rate, contrary to behavioural thresholds, which are known to vary inversely with the stimulation rate. Adaptation effects are therefore a confounding factor that must be accounted for when attempting to compare behavioural and objective measures.

Abstract

The electrically evoked compound action potential (ECAP) amplitude resulting from a train of pulses of finite duration (100 ms or 200 ms) was found to vary inversely to the stimulation rate (pulse rate), corroborating well with neural adaptation results from a previous study (Dillier et al., 2005). Amplitude growth functions based on these adapted responses yield thresholds (TNRT) that increase with increasing pulse rate, contrary to behavioural thresholds, which are known to vary inversely with the stimulation rate. Adaptation effects are therefore a confounding factor that must be accounted for when attempting to compare behavioural and objective measures.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Otorhinolaryngology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2009
Deposited On:30 Mar 2009 06:53
Last Modified:05 Apr 2016 13:11
Publisher:Wiley-Blackwell
ISSN:1467-0100
Publisher DOI:https://doi.org/10.1002/cii.388
PubMed ID:19194964

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